Clomifene citrate
Data Sheet
For research use only. Not for human use.
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| CAS No. | 50-41-9 | Cat. No. | BCP03057 |
| Name | Clomifene citrate | ||
| Synonyms | Clomid;Serophene;Milophene;Serophene; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C26H28ClNO.C6H8O7 | M. Wt | 598.08 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Clomifene Citrate(CC) acted as an estrogen antagonist regardless of the concentration of E2 added together. In conclusion, CC acts as an estrogen agonist/antagonist via ER alpha in a coexisting estrogen concentration-dependent way whereas it acts as an estrogen antagonist via ER beta whether or not estrogen is present . Clomiphene was effective in increasing pregnancy rate compared to placebo (OR 5.8, 95% CI 1.6 to 21.5) as was clomiphene plus dexamethasone treatment (OR 9.46, 95% CI 5.1 to 17.7) compared to clomiphene alone. A significant improvement in the pregnancy rate was reported for clomiphene plus combined oral contraceptives versus clomiphene alone. No evidence of a difference in effect on pregnancy rate was found with any of the other comparisons . | ||
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