Equol

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP13598CAS No. ：531-95-3Purity：98%

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CAS No.	531-95-3	Cat. No.	BCP13598
Name	Equol
Synonyms	(-)-(S)-Equol; (S)-3-(4-Hydroxyphenyl)chroman-7-ol;(S)-Equol; S-Equol; (-)-(S)-Equol;Equol, (-)-;
SMILES
Chemical Name
Formula	C15H14O3	M. Wt	242.27
Purity	98%	Storage	Store at 4-8°C
Description	S-equol is an orally bioavailable, non-steroidal estrogen naturally produced by the metabolism of the isoflavonoid daidzein by human intestinal microflora, with potential chemoprotective and estrogen receptor (ER) modulating activities. S-equol preferentially binds to and activates the beta isoform of ER in certain target tissues, while having an antagonistic effect in other tissues. This modulates the expression of ER-responsive genes in a tissue-specific manner. This agent may increase bone mineral density, affect vasomotor symptoms, and may decrease the proliferation rate of susceptible cancer cells. In addition, this agent interferes with the activity of enzymes involved in steroid biosynthesis. S-equol inhibits dihydrotestosterone (DHT) production and may inhibit the proliferation of androgen-driven prostate cancer. S-equol is the biologically active enantiomer while R-equol is essentially inactive and has a weak affinity for alpha-ER.