Phenethyl caffeate New
Data Sheet
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| CAS No. | 104594-70-9 | Cat. No. | BCP27877 |
| Name | Phenethyl caffeate | ||
| Synonyms | Caffeic acid phenethyl ester;Phenylethyl caffeate; | ||
| SMILES | C1=CC=C(C=C1)CCOC(=O)C=CC2=CC(=C(C=C2)O)O | ||
| Chemical Name | |||
| Formula | C17H16O4 | M. Wt | 284.31 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Caffeic Acid Phenethyl Ester is the phenethyl alcohol ester of caffeic acid and a bioactive component of honeybee hive propolis, with antineoplastic, cytoprotective and immunomodulating activities. Upon administration, caffeic acid phenethyl ester (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways. In addition, CAPE inhibits PDGF-induced proliferation of vascular smooth muscle cells through the activation of p38 mitogen-activated protein kinase (MAPK) and hypoxia-inducible factor (HIF)-1alpha and subsequent induction of heme oxygenase-1 (HO-1). | ||
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