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Pogostone Chemical Structure

Pogostone

Data Sheet For research use only. Not for human use.
Cat. No. :BCP49696CAS No. :23800-56-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 23800-56-8 Cat. No. BCP49696
Name Pogostone
Synonyms Dhelwangin;4-Hydroxy-6-methyl-3-(4-methyl-1-oxopentyl)-2H-pyran-2-one;
SMILES CC1=CC(=C(C(=O)O1)C(=O)CCC(C)C)O
Chemical Name
Formula C12H16O4 M. Wt 224.25
Purity 98% Storage Store at 4-8°C
Description Pogostone, isolated from the herbs of Pogostemon cablin (Blanco) Benth, possesses potent anti-bacterial and anti-fungal activities and has been used for the quality control of essential oil of Pogostemon cablin. It could inhibit both gram negative bacteria (0.098-1 600 µg/ml) and gram positive bacteria (0.098-800 µg/ml). Besides, Pogostone could exert a gastro-protective effect against gastric ulceration, and the underlying mechanism might be associated with the stimulation of PGE2, improvement of antioxidant and anti-inflammatory status, as well as preservation of NP-SH. Pogostone exhibited an immunosuppressive property by directly blocking T cell proliferation as well as altering inflammatory cytokine profile.
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