Tafenoquine succinate New
Data Sheet
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| CAS No. | 106635-81-8 | Cat. No. | BCP44136 |
| Name | Tafenoquine succinate | ||
| Synonyms | WR 238605 Succinatee; WR-238605, WR 238605, WR238605, SB-252263-AAB; SB252263-AAB; SB 252263-AAB; | ||
| SMILES | CC1=CC(=NC2=C1C(=C(C=C2NC(C)CCCN)OC)OC3=CC=CC(=C3)C(F)(F)F)OC.C(CC(=O)O)C(=O)O | ||
| Chemical Name | |||
| Formula | C28H34F3N3O7 | M. Wt | 581.58 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Tafenoquine Succinate is an 8-aminoquinoline. Tafenoquine, also known as WR-238605, is an oral active antimalaria drug that is being investigated as a potential treatment for malaria, as well as for malaria prevention. Tafenoquine Shows Activity against Trypanosoma brucei. Tafenoquine targets leishmania respiratory complex III and induces apoptosis. Tafenoquine has a long half-life of approximately 14 days and is generally safe and well tolerated, Malaria remains an important cause of global morbidity and mortality. As antimalarial drug resistance escalates, new safe and effective medications are necessary to prevent and treat malarial infection. | ||
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