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Tafenoquine succinate Chemical Structure

Tafenoquine succinate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP44136CAS No. :106635-81-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 106635-81-8 Cat. No. BCP44136
Name Tafenoquine succinate
Synonyms WR 238605 Succinatee; WR-238605, WR 238605, WR238605, SB-252263-AAB; SB252263-AAB; SB 252263-AAB;
SMILES CC1=CC(=NC2=C1C(=C(C=C2NC(C)CCCN)OC)OC3=CC=CC(=C3)C(F)(F)F)OC.C(CC(=O)O)C(=O)O
Chemical Name
Formula C28H34F3N3O7 M. Wt 581.58
Purity 98% Storage Store at 4-8°C
Description Tafenoquine Succinate is an 8-aminoquinoline. Tafenoquine, also known as WR-238605, is an oral active antimalaria drug that is being investigated as a potential treatment for malaria, as well as for malaria prevention. Tafenoquine Shows Activity against Trypanosoma brucei. Tafenoquine targets leishmania respiratory complex III and induces apoptosis. Tafenoquine has a long half-life of approximately 14 days and is generally safe and well tolerated, Malaria remains an important cause of global morbidity and mortality. As antimalarial drug resistance escalates, new safe and effective medications are necessary to prevent and treat malarial infection.
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