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Radicicol Chemical Structure

Radicicol

Data Sheet For research use only. Not for human use.
Cat. No. :BCP49026CAS No. :12772-57-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 12772-57-5 Cat. No. BCP49026
Name Radicicol
Synonyms Monorden;Monorden A;
SMILES CC1CC2C(O2)C=CC=CC(=O)CC3=C(C(=CC(=C3Cl)O)O)C(=O)O1
Chemical Name
Formula C18H17ClO6 M. Wt 364.78
Purity 98% Storage Store at 4-8°C
Description Radicicol is an inhibitor of Hsp90 with an IC50 value < 1 μM, and leads to proteasomal degradation. Radicicol exhibits inhibition on PDK with IC50s of 230 μM (PDK1) and 400 μM (PDK3). Radicicol is an antifungal and antimalarial antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB. Radicicol is also an inhibitor of fat mass and obesity-associated protein (FTO), with an IC50 value of 16.04 μM.
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