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Tegatrabetan Chemical Structure

Tegatrabetan

Data Sheet For research use only. Not for human use.
Cat. No. :BCP32893CAS No. :1227637-23-1Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1227637-23-1 Cat. No. BCP32893
Name Tegatrabetan
Synonyms BC2059; BC-2059; BC 2059;Tegavivint;
SMILES CC1CC(CN(C1)S(=O)(=O)C2=CC3=C(C=C2)C(=C4C=CC(=CC4=C3N=O)S(=O)(=O)N5CC(CC(C5)C)C)NO)C
Chemical Name
Formula C28H36N4O6S2 M. Wt 588.74
Purity 98% Storage Store at 4-8°C
Description Tegatrabetan is an orally bioavailable and potent β-catenin inhibitor. BC2059 potently induces apoptosis as a single agent and in combination with bortezomib in multiple myeloma. BC2059 induced apoptosis in 10/10 genetically heterogeneous human myeloma cell lines (HMCL) treated with dosages ranging from 50-500nM.
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