ICG-001 Discount

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP02465CAS No. ：847591-62-2Purity：98%

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CAS No.	847591-62-2	Cat. No.	BCP02465
Related Products	1422253-38-0（PRI-724） 780757-88-2（ICG-001）
Name	ICG-001
Synonyms	ICG 001; ICG001;PRI-724;PRI724; PRI 724; ICG001 isomer; ICG-001 isomer; ICG 001 isomer;
SMILES	C1CN(C2CN(C(=O)C(N2C1=O)CC3=CC=C(C=C3)O)CC4=CC=CC5=CC=CC=C54)C(=O)NCC6=CC=CC=C6
Chemical Name
Formula	C33H32N4O4	M. Wt	548.63
Purity	98%	Storage	Store at 4-8°C
Description	PRI-724, an isomer or enantiomer of ICG-001, is a potent, specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity. Wnt signaling pathway inhibitor PRI-724 specifically inhibits the recruiting of beta-catenin with its coactivator CBP (the binding protein of the cAMP response element-binding protein CREB); together with other transcription factors beta-catenin/CBP binds to WRE (Wnt-responsive element) and activates transcription of a wide range of target genes of Wnt/beta-catenin signaling. Note: ICG-001 and PRR-724 are not the same molecule, which are enantiomer isomers. Many vendors confused them.