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CAS No. | 1252362-53-0 | Cat. No. | BCP47054 |
Name | LRE1 | ||
Synonyms | T15787; T-15787; T 15787; | ||
SMILES | C1CC1N(CC2=CC=CS2)C3=CC(=NC(=N3)N)Cl | ||
Chemical Name | |||
Formula | C12H13ClN4S | M. Wt | 280.78 |
Purity | 98% | Storage | Store at 4-8°C |
Description | LRE1 is an allosteric soluble adenylyl cyclase (sAC)-specific inhibitor (IC50 value ≤ 10μM) that prevents sAC-dependent processes in cellular and physiological systems via occupying the binding site of the physiological activator HCO3-. LRE1 also inhibits cAMP accumulation in 4-4 cells (IC50 value 11 μM). |
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