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CAS No. | 330676-02-3 | Cat. No. | BCP40647 |
Name | KH 7 | ||
Synonyms | KH7; KH-7; | ||
SMILES | CC(C(=O)NN=CC1=C(C=CC(=C1)Br)O)SC2=NC3=CC=CC=C3N2 | ||
Chemical Name | |||
Formula | C17H15BrN4O2S | M. Wt | 419.28 |
Purity | 98% | Storage | Store at 4-8°C |
Description | KH 7 is a novel and selective inhibitor of soluble adenylyl cyclase (Sac) with IC50 value of 3 - 10 μM in vivo, which is an essential component of cAMP-signaling and is ubiquitously expressed. It blocks cAMP synthesis and shows an antiapoptotic effect at concentrations of 1 - 100 μM. |
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