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CAS No. | 130089-98-4 | Cat. No. | BCP24908 |
Name | NQ-301 | ||
Synonyms | NQ 301; NQ301; | ||
SMILES | CC(=O)C1=CC=C(C=C1)NC2=C(C(=O)C3=CC=CC=C3C2=O)Cl | ||
Chemical Name | |||
Formula | C18H12ClNO3 | M. Wt | 325.75 |
Purity | 98% | Storage | Store at 4-8°C |
Description | NQ-301 is a Selective CD45 inhibitor with Antiplatelet and antithrombotic activities (IC50 = 200 nM). NQ301 inhibits thromboxane A2 receptor and synthase activity in rabbit platelets. The antiplatelet activity of NQ301 may be mediated by inhibition of cytosolic Ca2+ mobilization, enhancement of cAMP production and inhibition of ATP secretion in activated platelets. |
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