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NQ-301 Chemical Structure

NQ-301

Data Sheet For research use only. Not for human use.
Cat. No. :BCP24908CAS No. :130089-98-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 130089-98-4 Cat. No. BCP24908
Name NQ-301
Synonyms NQ 301; NQ301;
SMILES CC(=O)C1=CC=C(C=C1)NC2=C(C(=O)C3=CC=CC=C3C2=O)Cl
Chemical Name
Formula C18H12ClNO3 M. Wt 325.75
Purity 98% Storage Store at 4-8°C
Description NQ-301 is a Selective CD45 inhibitor with Antiplatelet and antithrombotic activities (IC50 = 200 nM). NQ301 inhibits thromboxane A2 receptor and synthase activity in rabbit platelets. The antiplatelet activity of NQ301 may be mediated by inhibition of cytosolic Ca2+ mobilization, enhancement of cAMP production and inhibition of ATP secretion in activated platelets.
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