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CAS No. | 1345982-69-5 | Cat. No. | BCP17155 |
Name | Linerixibat | ||
Synonyms | GSK2330672;GSK-2330672;GSK 2330672; | ||
SMILES | CCCCC1(CS(=O)(=O)C2=C(C=C(C(=C2)CNC(CC(=O)O)CC(=O)O)OC)C(N1)C3=CC=CC=C3)CC | ||
Chemical Name | |||
Formula | C28H38N2O7S | M. Wt | 546.68 |
Purity | 98% | Storage | Store at 4-8°C |
Description | GSK2330672 is a highly potent, nonabsorbable ASBT(apical sodium-dependent bile acid transporter) inhibitor (hASBT IC50=42 ± 3 nM) which lowers glucose in an animal model of type 2 diabetes and shows excellent developability properties for evaluating the potential therapeutic utility of a nonabsorbable ASBT inhibitor for treatment of patients with type 2 diabetes. |
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