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L-660711 Chemical Structure

L-660711

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP30001CAS No. ：135028-15-8Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 135028-15-8 Cat. No. BCP30001
Name L-660711
Synonyms L660711;L 660711;MK-571;MK571;MK 571; (E)-5-(3-(2-(7-chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoic acid;
SMILES CN(C)C(=O)CCSC(C1=CC=CC(=C1)C=CC2=NC3=C(C=CC(=C3)Cl)C=C2)SCCC(=O)O
Chemical Name
Formula C26H27ClN2O3S2 M. Wt 515.09
Purity 98% Storage Store at 4-8°C
Description MK-571 is a potent CysLT1 (LTD4) leukotriene receptor inverse agonist (EC50 = 1.3 nM). Antagonizes LTD4-induced contractions of guinea pig trachea and ileum (pA2 values are 9.4 and 10.5 respectively). Also inhibitor of multidrug resistance protein-1 (MRP1) mediated transport; in vitro augments the effects of cytotoxic agents on malignant cells.
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