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MK-5172 Chemical Structure

MK-5172

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP28567CAS No. ：1350514-68-9Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1350514-68-9 Cat. No. BCP28567
Name MK-5172
Synonyms MK 5172; MK5172; Grazoprevir;
SMILES COC1=CC2=C(N=C(CCCCC[C@@H]3C[C@]3OC4=O)C(O[C@]5CN(C([C@](C(C)(C)C)N4)=O)[C@](C(N[C@@]([C@@H]6C=C)(C6)C(NS(C7CC7)(=O)=O)=O)=O)C5)=N2)C=C1
Chemical Name
Formula C38H50N6O9S M. Wt 766.91
Purity 98% Storage Store at 4-8°C
Description MK-5172, also known as Grazoprevir, is a drug approved for the treatment of hepatitis C. It was developed by Merck and completed Phase III trials, following promising results in Phase II when used in combination with the NS5A replication complex inhibitor elbasvir, either with or without ribavirin.Grazoprevir is a second generation hepatitis C virus protease inhibitor acting at the NS3/4a protease targets. It has good activity against a range of HCV genotype variants, including some that are resistant to most currently used antiviral medications.
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