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Duloxetine HCl Chemical Structure

Duloxetine HCl

Data Sheet For research use only. Not for human use.
Cat. No. :BCP06975CAS No. :136434-34-9Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 136434-34-9 Cat. No. BCP06975
Related Products 116539-59-4(Duloxetine) 116539-60-7((R)-Duloxetine) 116817-11-9((RS)-Duloxetine hydrochloride)
Name Duloxetine HCl
Synonyms Duloxetine hydrochloride;
SMILES CNCCC(C1=CC=CS1)OC2=CC=CC3=CC=CC=C32.Cl
Chemical Name
Formula C18H20ClNOS M. Wt 333.88
Purity 98% Storage Store at 4-8°C
Description Duloxetine Hydrochloride is the hydrochloride salt of duloxetine, a fluoxetine derivative belonging to the class of selective serotonin (5-HT) and norepinephrine (NE) reuptake inhibitors (SSNRIs) and exhibiting antidepressant activity. Duloxetine selectively prevents the reuptake of 5-HT and NE via transporter complexes on the pre-synaptic membrane, thereby increasing the level of these neurotransmitters within the synaptic cleft. As a result, this agent potentiates serotonergic and noradrenergic activities in the central nervous system, and alleviates depression and neuropathy sensations, such as pain and tingling. Furthermore, duloxetine does not show significant affinity for dopaminergic, adrenergic, cholinergic, histaminergic, opioid, glutamate, and gamma-aminobutyric acid (GABA) receptors.
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