Telotristat besilate
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CAS No. | 1374745-52-4 | Cat. No. | BCP16704 |
Name | Telotristat besilate | ||
Synonyms | LP-778902 besilate; LP 778902 besilate; LP778902 besilate; | ||
SMILES | CC1=NN(C=C1)C2=C(C=CC(=C2)Cl)C(C(F)(F)F)OC3=NC(=NC(=C3)C4=CC=C(C=C4)CC(C(=O)O)N)N.C1=CC=C(C=C1)S(=O)(=O)O | ||
Chemical Name | |||
Formula | C31H28ClF3N6O6S | M. Wt | 705.1 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Telotristat besilate is a tryptophan hydroxylase inhibitor.Telotristat, also known as LP-778902, is the acid form of Telotristat ethyl, and the active metabolite of LX1606 (Telotristat etiprate), which is an orally bioavailable, small-molecule, tryptophan hydroxylase (TPH) inhibitor and serotonin synthesis inhibitor with potential antiserotonergic activity. Blocking peripheral serotonin synthesis by telotristat reduces severity of both chemical- and infection-induced intestinal inflammation. |
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