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Telotristat besilate Chemical Structure

Telotristat besilate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP16704CAS No. :1374745-52-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1374745-52-4 Cat. No. BCP16704
Name Telotristat besilate
Synonyms LP-778902 besilate; LP 778902 besilate; LP778902 besilate;
SMILES CC1=NN(C=C1)C2=C(C=CC(=C2)Cl)C(C(F)(F)F)OC3=NC(=NC(=C3)C4=CC=C(C=C4)CC(C(=O)O)N)N.C1=CC=C(C=C1)S(=O)(=O)O
Chemical Name
Formula C31H28ClF3N6O6S M. Wt 705.1
Purity 98% Storage Store at 4-8°C
Description Telotristat besilate is a tryptophan hydroxylase inhibitor.Telotristat, also known as LP-778902, is the acid form of Telotristat ethyl, and the active metabolite of LX1606 (Telotristat etiprate), which is an orally bioavailable, small-molecule, tryptophan hydroxylase (TPH) inhibitor and serotonin synthesis inhibitor with potential antiserotonergic activity. Blocking peripheral serotonin synthesis by telotristat reduces severity of both chemical- and infection-induced intestinal inflammation.
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