OTSSP167 hydrochloride
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1431698-10-0 | Cat. No. | BCP28086 |
| Related Products | 1431697-89-0（OTSSP167） | ||
| Name | OTSSP167 hydrochloride | ||
| Synonyms | OTSSP167 HCl; OTS167 HCl;OTSSP167; OTSSP-167; OTSSP 167; OTS167; OTS-167; OTS 167; | ||
| SMILES | ClC1=CC(C2=CC=C(N=CC(C(C)=O)=C3N[C@]4CC[C@](CN(C)C)CC4)C3=N2)=CC(Cl)=C1O.[H]Cl | ||
| Chemical Name | |||
| Formula | C25H29Cl3N4O2 | M. Wt | 523.88 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | OTSSP167, also known as OTS167, is an orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity. Upon administration, OTS167 binds to MELK, which prevents both MELK phosphorylation and activation; thus inhibiting the phosphorylation of downstream MELK substrates. This may lead to an inhibition of both cell proliferation and survival in MELK-expressing tumor cells. | ||
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