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CAS No. | 1441000-45-8 | Cat. No. | BCP48961 |
Name | Opiranserin | ||
Synonyms | VVZ-149;VVZ 149;VVZ149; | ||
SMILES | CCCCOC1=C(C=C(C=C1OC)C(=O)NCC2(CCOCC2)N(C)C)OC | ||
Chemical Name | |||
Formula | C21H34N2O5 | M. Wt | 394.51 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Opiranserin, a non-opioid and non-NSAID analgesic candidate, is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, respectively. Opiranserin shows antagonistic activity on rP2X3 (IC50=0.87 μM). Opiranserin is development as an injectable agent for the treatment of postoperative pain. |
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