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Opiranserin Chemical Structure

Opiranserin

Data Sheet For research use only. Not for human use.
Cat. No. :BCP48961CAS No. :1441000-45-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1441000-45-8 Cat. No. BCP48961
Name Opiranserin
Synonyms VVZ-149;VVZ 149;VVZ149;
SMILES CCCCOC1=C(C=C(C=C1OC)C(=O)NCC2(CCOCC2)N(C)C)OC
Chemical Name
Formula C21H34N2O5 M. Wt 394.51
Purity 98% Storage Store at 4-8°C
Description Opiranserin, a non-opioid and non-NSAID analgesic candidate, is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, respectively. Opiranserin shows antagonistic activity on rP2X3 (IC50=0.87 μM). Opiranserin is development as an injectable agent for the treatment of postoperative pain.
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