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Siramesine Chemical Structure

Siramesine

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP08745CAS No. ：147817-50-3Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 147817-50-3 Cat. No. BCP08745
Related Products 224177-60-0（Siramesine hydrochloride）
Name Siramesine
Synonyms Lu-28-179; Lu 28-179; Lu28-179; Lu-28179; Lu 28179; Lu28179;
SMILES FC1=CC=C(N2C=C(CCCCN3CCC4(CC3)OCC5=C4C=CC=C5)C6=C2C=CC=C6)C=C1
Chemical Name
Formula C30H31FN2O M. Wt 454.58
Purity 98% Storage Store at 4-8°C
Description Siramesine, also known as Lu-28-179, is a potent sigma-2 receptor agonist. Siramesine triggers cell death through destabilisation of mitochondria, but not lysosomes. Siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation. Siramesine involves lysosomal leakage and oxidative stress.
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LCMS H-NMR
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