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Blarcamesine hydrochloride Chemical Structure

Blarcamesine hydrochloride

Data Sheet For research use only. Not for human use.
Cat. No. :BCP24794CAS No. :195615-84-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 195615-84-0 Cat. No. BCP24794
Name Blarcamesine hydrochloride
Synonyms AVex-73 hydrochloride;Anavex-2-73 HCl;Anavex 2-73; Anavex2-73; Anavex 2-73; Anavex-273; Anavex273; Anavex 273; AE-37 hydrochloride;
SMILES CN(C)CC1CCOC1(C2=CC=CC=C2)C3=CC=CC=C3.Cl
Chemical Name
Formula C19H24ClNO M. Wt 317.85
Purity 98% Storage Store at 4-8°C
Description Anavex2-73 is a muscarinic/σ1 ligand. ANAVEX2-73 (0.01-3.0 mg/kg i.p.) alleviated the scopolamine- and dizocilpine-induced learning impairments. ANAVEX2-73 (300 µg/kg) also reversed the learning deficits in mice injected with Aβ(25-35) peptide, a non-transgenic Alzheimer's disease model. The neuroprotective activity of ANAVEX2-73, its mixed cholinergic/σ(1) activity, its low active dose range and its long duration of action together reinforce its therapeutic potential in Alzheimer's disease.
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