Pleconaril

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP20819CAS No. ：153168-05-9Purity：98%

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CAS No.	153168-05-9	Cat. No.	BCP20819
Name	Pleconaril
Synonyms	SR-263843; SR-63843; VP-63843; Win-63843; SR263843; SR63843; VP63843; Win63843; SR 263843; SR 63843; VP 63843; Win 63843;
SMILES	CC1=C(OCCCC2=CC(C)=NO2)C(C)=CC(C3=NOC(C(F)(F)F)=N3)=C1
Chemical Name
Formula	C18H18F3N3O3	M. Wt	381.35
Purity	98%	Storage	Store at 4-8°C
Description	Pleconaril is an antiviral drug potentially for the treatment of enterovirus infection and asthma. Pleconaril, administered either orally or intranasally, is active against viruses in the Picornaviridae family, including Enterovirus and Rhinovirus.It has shown useful activity against the dangerous strain enterovirus D68. Pleconaril binds to a hydrophobic pocket in the VP1 protein. Pleconaril has been shown in viral assembly to associate with viral particles.[9] Through noncovalent, hydrophobic interactions compounds can bind to the hydrophobic pocket. Amino acids in positions Tyr152 and Val191 are a part of the VP1 drug binding pocket.