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Vipivotide tetraxetan Chemical Structure

Vipivotide tetraxetan

Data Sheet For research use only. Not for human use.
Cat. No. :BCP35795CAS No. :1702967-37-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1702967-37-0 Cat. No. BCP35795
Name Vipivotide tetraxetan
Synonyms PSMA-617; PSMA617; PSMA 617;
SMILES
Chemical Name
Formula C49H71N9O16 M. Wt 1042.15
Purity 98% Storage Store at 4-8°C
Description Vipivotide tetraxetan is a ligand used to make 177Lu-PSMA-617, which is a radioactive molecule to fight cancer. PSMA617 possesses a small peptide, which was designed to target prostate-specific membrane antigen (PSMA). PSMA617 demonstrates high radiolytic stability for at least 72 h. PSMA617 has high inhibition potency (equilibrium dissociation constant Ki=2.34±2.94 nM on LNCaP; Ki=0.37±0.21 nM enzymatically determined). 177 Lu-PSMA-617 offers a potential additional life-prolonging treatment option for men with mCRPC.
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