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CAS No. | 718612-49-8 | Cat. No. | BCP49629 |
Name | SN-38-D3 | ||
Synonyms | NK012-D3;[2H3]-SN-38; | ||
SMILES | CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=C1C=C(C=C5)O | ||
Chemical Name | |||
Formula | C22H20N2O5 | M. Wt | 392.4 |
Purity | 98% | Storage | Store at 4-8°C |
Description | SN-38-D3 is the deuterium labeled SN-38. SN-38 (NK012) is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 (NK012) inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. |
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