Abarelix New

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP27629CAS No. ：183552-38-7Purity：98%

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CAS No.	183552-38-7	Cat. No.	BCP27629
Name	Abarelix
Synonyms	PPI149; PPI-149; PPI 149; R3827; R-3827; R 3827;
SMILES	CC(C)CC(C(=O)NC(CCCCNC(C)C)C(=O)N1CCCC1C(=O)NC(C)C(=O)N)NC(=O)C(CC(=O)N)NC(=O)C(CC2=CC=C(C=C2)O)N(C)C(=O)C(CO)NC(=O)C(CC3=CN=CC=C3)NC(=O)C(CC4=CC=C(C=C4)Cl)NC(=O)C(CC5=CC6=CC=CC=C6C=C5)NC(=O)C
Chemical Name
Formula	C72H95ClN14O14	M. Wt	1416.08
Purity	98%	Storage	Store at 4-8°C
Description	Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth.