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Opigolix Chemical Structure

Opigolix

Data Sheet For research use only. Not for human use.
Cat. No. :BCP36620CAS No. :912587-25-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 912587-25-8 Cat. No. BCP36620
Name Opigolix
Synonyms ASP1707; ASP-1707; ASP 1707;
SMILES CC(C(=NS(=O)(=O)C1=C(C=CC(=C1)C(=C(C2=NC3=CC=CC=C3N2)C(=O)C4=C(C=CC(=C4)F)F)O)F)N)O
Chemical Name
Formula C25H19F3N4O5S M. Wt 544.5
Purity 98% Storage Store at 4-8°C
Description Opigolix, also known as ASP1707, is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist (GnRH antagonist) which was under development by Astellas Pharma for the treatment of endometriosis and rheumatoid arthritis. It was also under investigation for the treatment of prostate cancer. It reached phase II clinical trials for both endometriosis and rheumatoid arthritis prior to the discontinuation of its development in April 2018.
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