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CAS No. | 1931994-81-8 | Cat. No. | BCP44094 |
Name | Zabedosertib | ||
Synonyms | BAY 1834845; BAY1834845; BAY-1834845; | ||
SMILES | CC(C)(C1=CC2=NN(C=C2C=C1NC(=O)C3=NC(=CC=C3)C(F)(F)F)CCS(=O)(=O)C)O | ||
Chemical Name | |||
Formula | C20H21F3N4O4S | M. Wt | 470.47 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Zabedosertib, also known as BAY 1834845, is a IRAK-4 inhibitor. IRAK-4 inhibitors are an exciting therapeutic option in RA management because unlike other targeted disease-modifying agents, they target the innate immune system. The role of IRAK-4 as a key component of Toll/Interleukin-1 receptor signaling and its potential for a low rate of infectious complications is particularly exciting and this may facilitate their use in combination treatment. |
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