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CAS No. | 204205-90-3 | Cat. No. | BCP33949 |
Name | Indibulin | ||
Synonyms | ZIO 301;D 24851;ZIO301;D24851;ZIO-301;D-24851; | ||
SMILES | C1=CC=C2C(=C1)C(=CN2CC3=CC=C(C=C3)Cl)C(=O)C(=O)NC4=CC=NC=C4 | ||
Chemical Name | |||
Formula | C22H16ClN3O2 | M. Wt | 389.83 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Indibulin is a synthetic small molecule with antimitotic and potential antineoplastic activities. Indibulin binds to a site on tubulin that is different from taxane- or Vinca alkaloid-binding sites, destabilizing tubulin polymerization and inducing tumor cell cycle arrest and apoptosis. This agent has been shown to be active against multidrug-resistant (MDR) and taxane- resistant tumor cell lines. Check for active clinical trials or closed clinical trials using this agent. |
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