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CAS No. | 2055397-28-7 | Cat. No. | BCP29433 |
Name | WM-1119 | ||
Synonyms | MOZ-IN-1; WM 1119; WM1119; | ||
SMILES | O=C(NNS(=O)(C1=CC=CC=C1F)=O)C2=CC(C3=NC=CC=C3)=CC(F)=C2 | ||
Chemical Name | |||
Formula | C18H13F2N3O3S | M. Wt | 389.38 |
Purity | 98% | Storage | Store at 4-8°C |
Description | WM-1119 is a highly potent, selective inhibitor of lysine acetyltransferase KAT6A with Kd of 2 nM, WM-1119 is a reversible competitor of acetyl coenzyme A and inhibits MYST-catalysed histone acetylation. WM-1119 induces cell cycle exit and cellular senescence without causing DNA damage. WM-1119 arrests the progression of lymphoma in mice. |
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