BMS-1166 hydrochloride New
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CAS No. | 2113650-05-6 | Cat. No. | BCP31309 |
Name | BMS-1166 hydrochloride | ||
Synonyms | BMS 1166 Hydrochloride; BMS1166 Hydrochloride; BMS-1166 HCl; BMS 1166 HCl; BMS1166 HCl; | ||
SMILES | O=C(O)[C@@H]1N(CC2=CC(Cl)=C(OCC3=CC=CC(C4=CC=C(OCCO5)C5=C4)=C3C)C=C2OCC6=CC=CC(C#N)=C6)C[C@H](O)C1.Cl | ||
Chemical Name | |||
Formula | C36H34Cl2N2O7 | M. Wt | 677.57 |
Purity | 98% | Storage | Store at 4-8°C |
Description | BMS-1166 hydrochloride is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation. |
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