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KEA1-97 Chemical Structure

KEA1-97

Data Sheet For research use only. Not for human use.
Cat. No. :BCP42477CAS No. :2138882-71-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2138882-71-8 Cat. No. BCP42477
Name KEA1-97
Synonyms KEA1 97; KEA197;KEA 1-97;
SMILES C1=CC(=CC=C1C2=CC=C(C=C2)F)NC3=NC(=NC(=N3)Cl)Cl
Chemical Name
Formula C15H9Cl2FN4 M. Wt 335.16
Purity 98% Storage Store at 4-8°C
Description KEA1-97 is a thioredoxin-caspase 3 interaction disruptor. It has been shown to impair breast cancer pathogenicity. KEA1-97 disrupts the interaction of thioredoxin with caspase 3, activates caspases, and induces apoptosis without affecting thioredoxin activity. Moreover, KEA1-97 impairs in vivo breast tumor xenograft growth.
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