SRX3177 New
Data Sheet
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| CAS No. | 2241237-51-2 | Cat. No. | BCP48567 |
| Name | SRX3177 | ||
| Synonyms | SRX-3177; SRX 3177; | ||
| SMILES | O=C(C1=CC2=CN=C(NC3=CC=C(C4=CSC5=C4OC(N6CCOCC6)=CC5=O)C=C3)N=C2N1C7CCCC7)N(C)C | ||
| Chemical Name | |||
| Formula | C31H32N6O4S | M. Wt | 584.69 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | SRX3177 is a triple inhibitor of CDK, PI3K, and BRD4, with IC50s of 33 nM (BRD4 BD1), 89 nM (BRD4 BD2), 79 nM (PI3Kα), 83 nM (PI3Kδ), 3.18 μM (PI3Kγ), <2.5 nM (CDK4), 3.3 nM (CDK6), respectively. SRX3177 exerts broad cytotoxic activity against cancer cells, but acts friendly with normal epithelial cells. | ||
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