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CAS No. | 253310-42-8 | Cat. No. | BCP44394 |
Name | BMS 195614 | ||
Synonyms | BMS195614;BMS-195614; | ||
SMILES | CC1(CC=C(C2=C1C=CC(=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)C4=CC5=CC=CC=C5N=C4)C | ||
Chemical Name | |||
Formula | C29H24N2O3 | M. Wt | 448.51 |
Purity | 98% | Storage | Store at 4-8°C |
Description | BMS 195614 is a neutral RAR α-selective antagonist (Ki = 2.5 nM) and exhibits no significant effect on nuclear receptor corepressor (NCoR) binding. BMS 195614 moderately decreases SMRT binding to RAR and agonist-induced coactivator (CoA) recruitment. Also it is a derivative of retinoic acid. |
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