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9-cis-Retinoic acid Chemical Structure

9-cis-Retinoic acid

Data Sheet For research use only. Not for human use.
Cat. No. :BCP27899CAS No. :5300-03-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 5300-03-8 Cat. No. BCP27899
Name 9-cis-Retinoic acid
Synonyms ALRT1057;ALRT 1057;ALRT-1057;Alitretinoin;9-cis-Tretinoin;Panretin;
SMILES CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
Chemical Name
Formula C20H28O2 M. Wt 300.43
Purity 98% Storage Store at 4-8°C
Description 9-cis-Retinoic acid is a form of vitamin A. Alitretinoin is an orally- and topically-active naturally-occurring retinoic acid with antineoplastic, chemopreventive, teratogenic, and embryotoxic activities. Alitretinoin binds to and activates nuclear retinoic acid receptors (RAR) and retinoid X receptors (RXR); these activated receptors act as transcription factors, regulating gene expression that results in the inhibition of cell proliferation, induction of cell differentiation, and apoptosis of both normal cells and tumor cells.
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