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Garsorasib Chemical Structure

Garsorasib

Data Sheet For research use only. Not for human use.
Cat. No. :BCP49682CAS No. :2559761-14-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2559761-14-5 Cat. No. BCP49682
Name Garsorasib
Synonyms
SMILES CC1CN(C(CN1C(=O)C=C)C)C2=NC(=O)N(C3=NC(=C(C=C32)F)C4=C(C=CC=C4F)N)C5=C(N=CN=C5C6CC6)C7CC7
Chemical Name
Formula C32H32F2N8O2 M. Wt 598.65
Purity 98% Storage Store at 4-8°C
Description Garsorasib is an orally available inhibitor of the oncogenic KRAS substitution mutation, G12C, with potential antineoplastic activity. Upon oral administration, garsorasib selectively targets the KRAS G12C mutant and inhibits KRAS G12C mutant-dependent signaling. KRAS, a member of the RAS family of oncogenes, serves an important role in cell signaling, division and differentiation. Mutations of KRAS may induce constitutive signal transduction leading to tumor cell growth, proliferation, invasion, and metastasis.
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