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CAS No. | 2716890-91-2 | Cat. No. | BCP46442 |
Name | CHD1Li6.11 | ||
Synonyms | |||
SMILES | CC1=CC(=NC(=N1)N2CCCC2)NC3=CC=C(C=C3)NC(=O)CC4=CC(=CS4)Br | ||
Chemical Name | |||
Formula | C21H22BrN5OS | M. Wt | 472.4 |
Purity | 98% | Storage | Store at 4-8°C |
Description | CHD1Li 6.11 is a potent oncogenic CHD1L inhibitor (IC50=3.3 µM for cat-CHD1L recombinant protein). CHD1Li 6.11 is an orally bioavailable antitumor agent, significantly reducing the tumor volume of CRC xenografts generated from isolated quasi mesenchymal cells (M-phenotype), which possess enhanced tumorigenic properties. |
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