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CAS No. | 2734909-87-4 | Cat. No. | BCP48318 |
Related Products | 54447-84-6(c-di-AMP) | ||
Name | c-di-AMP disodium | ||
Synonyms | Cyclic diadenylate disodium; Cyclic-di-AMP disodium; | ||
SMILES | |||
Chemical Name | |||
Formula | C20H22N10Na2O12P2 | M. Wt | 702.38 |
Purity | 98% | Storage | Store at 4-8°C |
Description | c-di-AMP sodium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP sodium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP sodium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses. |
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