(±)-SLV319 New
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CAS No. | 362519-49-1 | Cat. No. | BCP30069 |
Name | (±)-SLV319 | ||
Synonyms | (±)-BMS-646256; (±)-BMS646256; (±)-BMS 646256; (±)-SLV-319; (±)-SLV 319; SLV319; (±)-JD-5001; (±)-JD 5001; (±)-JD5001; (±)-Ibipinabant; | ||
SMILES | CN=C(NS(=O)(=O)C1=CC=C(C=C1)Cl)N2CC(C(=N2)C3=CC=C(C=C3)Cl)C4=CC=CC=C4 | ||
Chemical Name | |||
Formula | C23H20Cl2N4O2S | M. Wt | 487.40 |
Purity | 98% | Storage | Store at 4-8°C |
Description | (±)-SLV319 is the racemate of SLV319. SLV319 is a potent and selective cannabinoid-1 (CB-1) receptor antagonist with an IC50 of 22 nM.Ibipinabant, also known as BMS-646256, JD-5001 and SLV-319, is a potent and highly selective CB1 antagonist. It has potent anorectic effects in animals, and was researched for the treatment of obesity, although CB1 antagonists as a class have now fallen out of favour as potential anorectics following the problems seen with rimonabant, and so ibipinabant is now only used for laboratory research, especially structure-activity relationship studies into novel CB1 antagonists. |
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