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CAS No. | 1818428-24-8 | Cat. No. | BCP43165 |
Name | EHP-101 | ||
Synonyms | EHP101; EHP 101; VCE-004; VCE004; VCE 004; VCE-004.8; VCE004.8; VCE 004.8; | ||
SMILES | CCCCCC1=C(C(=C(C(=O)C1=O)C2C=C(CCC2C(=C)C)C)O)NCC3=CC=CC=C3 | ||
Chemical Name | |||
Formula | C28H35NO3 | M. Wt | 433.58 |
Purity | 98% | Storage | Store at 4-8°C |
Description | EHP-101 (VCE-004.8) is an orally active, specific PPARγ and CB2 receptor dual agonist. EHP-101 inhibits prolyl-hydroxylases (PHDs) and activates the HIF pathway. EHP-101 attenuates adipogenesis and prevents diet-induced obesity. EHP-101 (20 mg/kg/day; i.p.; for 3 weeks) induces a significant reduction in body weight gain, total fat mass, adipocyte volume and plasma triglycerides levels in HFD mice. |
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