
Eriodictyol-7-O-glucoside New

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CAS No. | 38965-51-4 | Cat. No. | BCP23712 |
Name | Eriodictyol-7-O-glucoside | ||
Synonyms | Miscanthoside;Pyracanthoside; | ||
SMILES | C1C(OC2=CC(=CC(=C2C1=O)O)OC3C(C(C(C(O3)CO)O)O)O)C4=CC(=C(C=C4)O)O | ||
Chemical Name | |||
Formula | C21H22O11 | M. Wt | 450.39 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Eriodictyol 7-O-glucoside is a flavanone glucoside that has been found in V. coloratum and has diverse biological activities. It scavenges hydroxyl and superoxide anion radicals in cell-free assays (IC50s = 0.28 and 0.3 mM, respectively). Eriodictyol 7-O-glucoside activates nuclear factor E2-related factor 2 (Nrf2) in a reporter assay. It protects against cytotoxicity induced by cisplatin in human renal mesangial cells (HRMCs), but not A549 lung or MDA-MB-231 breast cancer cells, when used at a concentration of 80 µM. Eriodictyol 7-O-glucoside (30 mg/kg) attenuates neurological deficits and reduces infarct volume in a rat model of cerebral ischemia induced by middle cerebral artery occlusion (MCAO). |
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