D-DOPA New
Data Sheet
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| CAS No. | 5796-17-8 | Cat. No. | BCP44158 |
| Name | D-DOPA | ||
| Synonyms | |||
| SMILES | C1=CC(=C(C=C1CC(C(=O)O)N)O)O | ||
| Chemical Name | |||
| Formula | C9H11NO4 | M. Wt | 197.19 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | D-DOPA is the dextrorotary isomer of the dopamine precursor L-DOPA. It can be converted to L-DOPA via sequential oxidation and transamination, which are mediated by D-amino acid oxidase and DOPA transaminase, respectively, in rat kidney homogenates. It reduces the number of dopaminergic neurons in primary rat embryonic mesencephalic cultures in a concentration-dependent manner. Intraventricular administration of D-DOPA increases striatal dopamine levels in rats. D-DOPA induces contralateral turns in a rat model of Parkinson's disease induced by 6-OHDA. | ||
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