Cyclosporin B New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 63775-95-1 | Cat. No. | BCP04175 |
| Name | Cyclosporin B | ||
| Synonyms | Cyclosporine Impurity-B; Antibiotic S 7481F2;CyclosporinB; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C61H109N11O12 | M. Wt | 1188.61 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Cyclosporin B is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosuppressant activity. Cyclosporin B is a derivative of cyclosporin A that exhibits significantly less immunosuppressive activity. Cyclosporin B displays antiviral properties, inhibiting entry of hepatitis B into hepatocytes. Cyclosporin B also inhibits RANKL-induced TRAP phosphatase activity, inducing apoptosis in osteoclasts. | ||
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