Epalrestat New

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP04572CAS No. ：82159-09-9Purity：98%

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CAS No.	82159-09-9	Cat. No.	BCP04572
Name	Epalrestat
Synonyms	ONO-2235; ONO 2235; ONO2235; Sorbistat;
SMILES	CC(=CC1=CC=CC=C1)C=C2C(=O)N(C(=S)S2)CC(=O)O
Chemical Name
Formula	C15H13NO3S2	M. Wt	319.39
Purity	98%	Storage	Store at 4-8°C
Description	Epalrestat may affect or delay progression of the underlying disease process. Data from six clinical trials were evaluated, and it was determined that epalrestat 50 mg 3 times/day may improve motor and sensory nerve conduction velocity and subjective neuropathy symptoms as compared with baseline and placebo. Epalrestat may serve as a new therapeutic option to prevent or slow the progression of diabetic neuropathy. Epalrestat significantly increased the amplitude of 3 cpm waves on EGG and improved the spectral analytical parameters of heart rate variability. These findings suggest that epalrestat is useful for the treatment of diabetic gastroparesis . Epalrestat is a highly effective and safe agent for the treatment of diabetic neuropathy .