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Isoliquiritigenin Chemical Structure

Isoliquiritigenin

Data Sheet For research use only. Not for human use.
Cat. No. :BCP02312CAS No. :961-29-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 961-29-5 Cat. No. BCP02312
Name Isoliquiritigenin
Synonyms GU17;ISL;Isoliquiritigen;GU 17;GU-17;
SMILES C1=CC(=CC=C1C=CC(=O)C2=C(C=C(C=C2)O)O)O
Chemical Name
Formula C15H12O4 M. Wt 256.25
Purity 98% Storage Store at 4-8°C
Description Isoliquiritigenin may be effective in preventing diabetic complications through inhibiting rat lens aldose reductase with an IC50 of 320 nM and sorbitol accumulation in human red blood cells with an IC50 of 2.0 μM.Isoliquiritigenin may also serve as a skin-lightening agent by inhibiting mono- and diphenolase tyrosinase activities with an IC50 of 8.1 μM. Isoliquiritigenin induces cell cycle arrest and cell growth inhibition in DU145 and LNCaP prostate cancer cell lines. Isoliquiritigenin induces apoptosis of human gastric cancer MGC-803 cells through increasing the intracellular free calcium concentration and decreasing the mitochondrial transmembrane potential (Deltapsi(m)).
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