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PF 915275 Chemical Structure

PF 915275

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP28049CAS No. ：857290-04-1Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 857290-04-1 Cat. No. BCP28049
Name PF 915275
Synonyms PF-915275; PF915275;
SMILES N#CC1=CC=C(C2=CC=C(S(NC3=NC(N)=CC=C3)(=O)=O)C=C2)C=C1
Chemical Name
Formula C18H14N4O2S M. Wt 350.39
Purity 98% Storage Store at 4-8°C
Description PF-915275 is a potent and selective 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) inhibitor (Ki = 2.3 nM) PF-915275 inhibits the conversion of prednisone to prednisolone in human hepatocytes in vitro (EC50 = 15 nM) and has antidiabetic activity in vivo.
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