SCH-23390 maleate New
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CAS No. | 87134-87-0 | Cat. No. | BCP28944 |
Name | SCH-23390 maleate | ||
Synonyms | SCH23390 maleate; SCH 23390 maleate; | ||
SMILES | CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)Cl.C(=CC(=O)O)C(=O)O | ||
Chemical Name | |||
Formula | C17H19Cl2NO | M. Wt | 324.24 |
Purity | 98% | Storage | Store at 4-8°C |
Description | SCH-23390 is a potent dopamine receptor antagonist (Ki values are 0.2 nM and 0.3 nM at D1 and D5 receptor sub-types, respectively). SCH-23390 is also an agonist at 5-HT1C and 5-HT2C receptors in vitro (Ki values are 6.3 nM and 9.3 nM respectively). It blocks quinpirole-induced Kir3 (GIRK) currents (EC50 = 268 nM) independently of receptors. |
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