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Guaiacol Chemical Structure

Guaiacol

Data Sheet For research use only. Not for human use.
Cat. No. :BCP27082CAS No. :90-05-1Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 90-05-1 Cat. No. BCP27082
Name Guaiacol
Synonyms 2-Methoxyphenol;o-Methoxyphenol;2-Hydroxyanisole;
SMILES COC1=CC=CC=C1O
Chemical Name
Formula C7H8O2 M. Wt 124.14
Purity 98% Storage Store at 4-8°C
Description Guaiacol is a phenolic compound with a methoxy group and is the monomethyl ether of catechol. Guaiacol is readily oxidized by the heme iron of peroxidases including the peroxidase of cyclooxygenase (COX) enzymes. It therefore serves as a reducing co-substrate for COX reactions. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. It is a yellowish aromatic oil that is now commonly derived from guaiacum or wood creosote. It is used medicinally as an expectorant, antiseptic, and local anesthetic. Guaiacol is used in traditional dental pulp sedation, and has the property of inducing cell proliferation; guaiacol is a potent scavenger of reactive oxygen radicals and its radical scavenging activity may be associated with its effect on cell proliferation. Guaiacol is also used in the preparation of synthetic vanillin. Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin. Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma.
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