LXS-196 2HCl New
Data Sheet
For research use only. Not for human use.
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| CAS No. | LXS-196HCl | Cat. No. | BCP30427 |
| Name | LXS-196 2HCl | ||
| Synonyms | NVP-LXS196; NVPLXS196; NVP LXS196; LXS196; LXS-196; LXS 196; | ||
| SMILES | O=C(NC1=NC=CC=C1N2CCC(N)(CC2)C)C3=NC(C4=NC=CC=C4C(F)(F)F)=CN=C3N.[H]Cl.[H]Cl | ||
| Chemical Name | |||
| Formula | C22H25Cl2F3N8O | M. Wt | 544.15 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | LXS-196 is a potent and orally active protein kinase C inhibitor for the treatment of uveal melanoma. Upon oral administration, protein kinase C inhibitor LXS196 binds to and inhibits PKC, which prevents the activation of PKC-mediated signaling pathways. This may lead to the induction of cell cycle arrest and apoptosis in susceptible tumor cells. PKC, a serine/threonine protein kinase overexpressed in certain types of cancer cells, is involved in tumor cell differentiation, proliferation, invasion and survival. | ||
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