Talabostat isomer mesylate New
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CAS No. | TIM | Cat. No. | BCP38291 |
Name | Talabostat isomer mesylate | ||
Synonyms | |||
SMILES | B(C1CCCN1C(=O)C(C(C)C)N)(O)O.CS(=O)(=O)O | ||
Chemical Name | |||
Formula | C10H23BN2O6S | M. Wt | 310.18 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Talabostat mesylate is the orally bioavailable mesylate salt of an amino boronic dipeptide with antineoplastic and hematopoiesis- stimulating activities. By cleaving N-terminal Xaa-Pro or Xaa-Ala residues, talabostat inhibits dipeptidyl peptidases, such as fibroblast activation protein (FAP), resulting in the stimulation of cytokine and chemokine production and specific T-cell immunity and T-cell- dependent activity. This agent may also stimulate the production of colony stimulating factors, such as granulocyte colony stimulating factor (G-CSF), resulting in the stimulation of hematopoiesis. Dipeptidyl peptidases are involved in the activation of polypeptide hormones and chemokines. |
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