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Talabostat isomer mesylate Chemical Structure

Talabostat isomer mesylate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP38291CAS No. :TIMPurity:98%
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  • Chemical Properties&Biological Activity
CAS No. TIM Cat. No. BCP38291
Name Talabostat isomer mesylate
Synonyms
SMILES B(C1CCCN1C(=O)C(C(C)C)N)(O)O.CS(=O)(=O)O
Chemical Name
Formula C10H23BN2O6S M. Wt 310.18
Purity 98% Storage Store at 4-8°C
Description Talabostat mesylate is the orally bioavailable mesylate salt of an amino boronic dipeptide with antineoplastic and hematopoiesis- stimulating activities. By cleaving N-terminal Xaa-Pro or Xaa-Ala residues, talabostat inhibits dipeptidyl peptidases, such as fibroblast activation protein (FAP), resulting in the stimulation of cytokine and chemokine production and specific T-cell immunity and T-cell- dependent activity. This agent may also stimulate the production of colony stimulating factors, such as granulocyte colony stimulating factor (G-CSF), resulting in the stimulation of hematopoiesis. Dipeptidyl peptidases are involved in the activation of polypeptide hormones and chemokines.
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