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Merestinib Chemical Structure

Merestinib

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP06826CAS No. ：1206799-15-6Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1206799-15-6 Cat. No. BCP06826
Name Merestinib
Synonyms LY-2801653;LY 2801653;LY2801653;
SMILES
Chemical Name
Formula C30H22F2N6O3 M. Wt 552.53
Purity 98% Storage Store at 4-8°C
Description Merestinib, also known as LY2801653, is an orally available, small molecule inhibitor of the proto-oncogene c-Met (mesenchymal-epithelial transition, also known as hepatocyte growth factor receptor [HGFR]) with potential antineoplastic activity. c-Met inhibitor LY2801653 selectively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways. This may induce cell death in tumor cells overexpressing c-Met protein or expressing constitutively activated c-Met protein. This agent has potent anti-tumor efficacy in mono- and combination therapy in a broad range of cancers.
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H-NMR
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