Vicriviroc Malate
Data Sheet
For research use only. Not for human use.
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| CAS No. | 541503-81-5 | Cat. No. | BCP01856 |
| Name | Vicriviroc Malate | ||
| Synonyms | SCH 417690;SCH-D;SCH-417690;SCH417690; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C28H38F3N5O2.C4H6O5 | M. Wt | 667.72 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Vicriviroc has a higher binding affinity to CCR5 as opposed to SCH-C in competition binding assays. Vicriviroc is close to 6-fold less active than SCH-C in attenuating hERG current among In voltage-clamped L929 cells. Vicriviroc inhibits GTPγS binding to the membranes from HTS-hCCR5 cells induced by RANTES. Vicriviroc displays potent antiviral activity against a panel of 30 R5-tropic HIV-1 isolates. Vicriviroc possibly targets an early step in the viral life cycle prior to reverse transcription and virion maturation. | ||
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