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Vicriviroc Malate Chemical Structure

Vicriviroc Malate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP01856CAS No. :541503-81-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 541503-81-5 Cat. No. BCP01856
Name Vicriviroc Malate
Synonyms SCH 417690;SCH-D;SCH-417690;SCH417690;
SMILES
Chemical Name
Formula C28H38F3N5O2.C4H6O5 M. Wt 667.72
Purity 98% Storage Store at 4-8°C
Description Vicriviroc has a higher binding affinity to CCR5 as opposed to SCH-C in competition binding assays. Vicriviroc is close to 6-fold less active than SCH-C in attenuating hERG current among In voltage-clamped L929 cells. Vicriviroc inhibits GTPγS binding to the membranes from HTS-hCCR5 cells induced by RANTES. Vicriviroc displays potent antiviral activity against a panel of 30 R5-tropic HIV-1 isolates. Vicriviroc possibly targets an early step in the viral life cycle prior to reverse transcription and virion maturation.
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